Area,
I believe strongly in our current theory that PSSD, and PSSD cognitive/memory impairment, is caused by a desensitation of the 5ht1a post-synaptic receptor. This causes influx of the amino acid tryptophan which then interacts with sodium channels that cause the genital anesthesia symptoms. I believe only Lecozotan can cure this, but, despite the pharmaceutical giants spending millions of dollars to put the drug through phase III clinical trials, and the drug showing massive efficacy, it vaporized off the face of the earth under very suspicious circumstances. (possibly because it would undermine all their SSRI cashcow)
Anyway, let me get to my question. I would like to try one of the synthetic 5a-DHP substances by Idealabs as a way to increase Allopregnanolone. I wanted to see if this could possibly benefit the cognitive and memory impairments plaguing me. MY only concern is that the studies are half and half currently.
half the pubmed studies show that it reverses cognitive impairment to an extreme degree and is a miracle wonder.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232295/
https://www.ncbi.nlm.nih.gov/pubmed/21803451
https://www.ncbi.nlm.nih.gov/pubmed/20231471
https://www.ncbi.nlm.nih.gov/pubmed/21335664
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168882/
the OTHER half show that that it accelerates cognitive impairment and memory loss, and could even advance your brain into alzheimers disease.
https://www.ncbi.nlm.nih.gov/pubmed/22495347
https://www.ncbi.nlm.nih.gov/pubmed/26497250
https://www.ncbi.nlm.nih.gov/pubmed/17942736
https://www.ncbi.nlm.nih.gov/pubmed/24874172
https://www.ncbi.nlm.nih.gov/pubmed/14629930
1. Do you think that this substance can yield benefit for these PSSD issues?
2. why do the pubmed studies conflict? which version is reliable?
3. do you feel the product may be worth trying? or does it increase the risk of advancing the cognitive/memory impairment? is there a risk that it could advance the brain into alzheimers disease prematurely?
4. What is your opinion on this molecule?
Thank you, Brooks
I believe strongly in our current theory that PSSD, and PSSD cognitive/memory impairment, is caused by a desensitation of the 5ht1a post-synaptic receptor. This causes influx of the amino acid tryptophan which then interacts with sodium channels that cause the genital anesthesia symptoms. I believe only Lecozotan can cure this, but, despite the pharmaceutical giants spending millions of dollars to put the drug through phase III clinical trials, and the drug showing massive efficacy, it vaporized off the face of the earth under very suspicious circumstances. (possibly because it would undermine all their SSRI cashcow)
Anyway, let me get to my question. I would like to try one of the synthetic 5a-DHP substances by Idealabs as a way to increase Allopregnanolone. I wanted to see if this could possibly benefit the cognitive and memory impairments plaguing me. MY only concern is that the studies are half and half currently.
half the pubmed studies show that it reverses cognitive impairment to an extreme degree and is a miracle wonder.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232295/
https://www.ncbi.nlm.nih.gov/pubmed/21803451
https://www.ncbi.nlm.nih.gov/pubmed/20231471
https://www.ncbi.nlm.nih.gov/pubmed/21335664
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168882/
the OTHER half show that that it accelerates cognitive impairment and memory loss, and could even advance your brain into alzheimers disease.
https://www.ncbi.nlm.nih.gov/pubmed/22495347
https://www.ncbi.nlm.nih.gov/pubmed/26497250
https://www.ncbi.nlm.nih.gov/pubmed/17942736
https://www.ncbi.nlm.nih.gov/pubmed/24874172
https://www.ncbi.nlm.nih.gov/pubmed/14629930
1. Do you think that this substance can yield benefit for these PSSD issues?
2. why do the pubmed studies conflict? which version is reliable?
3. do you feel the product may be worth trying? or does it increase the risk of advancing the cognitive/memory impairment? is there a risk that it could advance the brain into alzheimers disease prematurely?
4. What is your opinion on this molecule?
Thank you, Brooks
Last edited by Brooks W. Esq on Sat Jan 07, 2017 11:45 am; edited 1 time in total