First I would like to say that I am new here and hope to be able to contribute well in this forum. I apologize for any grammatical mistakes, I myself come from Germany and translate most via google.
Now my story: (please read it, I'll try to be brief)
I've been dealing with genital numbness long before I've ever taken a psychotropic drug. I have had pronounced depression and anxiety since around 2012. My first antidepressant was fluoxetine, which I gave myself in the summer of 2015. I loved it at first: it did not make me feel negative things so strong but I was not a "zombie". It also seemed to improve my genital numbness, all worked fine. In conjunction with alcohol, it gave me a wonderful, light feeling that I will never forget. In the spring of 2016, I switched to fluvoxamine, as fluoxetine barely helped me against anxiety, and the effect seemed to be abating in general. I call it about a year until the spring of 2017. Since this also only weakly helped against fears, and also hardly any effect, I put it off. A few days later, I got genital feeling numbness, but at the time I still had a girl and a strong libido. I first came across PSSD but thought maybe my depression just came back and PSSD is a scientific hyphenation. The numbness improved fortunately within 2-3 months, at the end of the year my libido and feeling was more intense than ever. All I had to do was look at a woman's as and I was excited. My experience with drugs was rather positive until then.
Now comes the misery: In a clinic (where my libido was so good) I had Trazodone prescribed. I had constant sleep disturbances and fears, depression was well under control. I took 100 mg for one week, I got restless legs syndrome and could hardly sleep. My libido was fast in the basement, as I've never known it in my life. I did not know sexual discomfort until then. I still could get an erection, but orgasm was not so intense and my sperm was waterier than usual. I thought (unfortunately) I let the drug adjust something to my system. From the second week on was dosed to 200 mg, I was finally able to sleep. But I became so dizzy and generally uncomfortable with Trazodone. I really felt like a zombie, almost remotely controlled. It felt like acid was eating through my spine, as soon as I took the pills on my tongue she became numb. I also got spontaneous erections, but when I tried to do it on purpose, it barely worked. So I set off Trazodone after 9 days (7 * 100mg, 2 * 200mg).
My worst nightmare came true. I got genital numbness, my libido just did not return. I also noticed an emotional numbness. Since I knew PSSD really exists. I never thought that my life would be so changed by 11 stupid pills. I insisted on Trazodone because I wanted to prevent PSSD, and now I seem to have it. All I wanted to do was sleep again and not have any constant anxiety attacks anymore.
The withdraw is now 1 1/2 months ago. I still have almost no libido, and genital numbness. Also sometimes testicular pain. I feel cold and warmth, and pain, but hardly any normal touch. My theory is that it might have something to do with 5HT2 receptors. I have tolerated SSRI well until then and Trazodone very weakly inhibits serotonin, and only from higher doses. I was just 200, it can be dosed to 400. But it is a 5HT2 antagonist, and this activated is bad for anxiety but good for libido I read. And now I have no more anxiety since years. No SSRI und therapy helped me really at that point. But the price is no libido and numbness, it seams that Trazodone put a switch in the brain. Maybe it has something to do with dopamine receptor too, because I had restless legs under Trazo.
I am currently trying St. John's Wort to cure. Also Ginko, Maca, Omega3, Vitamin D and B12. It seems to help a little, but sports seem to help me the most. Sometimes I feel something like arousal again, but it's hardly fun because it feels so numb. I sometimes have brain zaps too, is that a good sign?